The FDA-approved dosing for tirzepatide (Mounjaro, Zepbound) follows a specific pattern:
Start with 2.5 mg once weekly for 4 weeks then increase to 5 mg once weekly for 4 weeks
Based on your results and tolerance, your doctor may increase your dose to:
- 5 mg once weekly (maintenance dose)
- 10 mg once weekly (higher dose)
- 15 mg once weekly (maximum dose)
Most people achieve significant weight loss results with the 5 mg, 10 mg, or 15 mg maintenance doses injected subcutaneously (under the skin) once weekly.
The best dose depends on your body's response and your weight loss goals. Clinical studies show that higher doses typically produce greater weight loss, but also may cause more side effects.
While some patients see excellent results at 5 mg weekly, others may need the maximum dose of 15 mg to achieve their weight loss targets. Your healthcare provider will help determine the right dose for you.
For those looking to maximize results, learning how to maximize weight loss on tirzepatide can help you get the most from your treatment.
Tirzepatide is just one medication for weight loss. If you're considering alternatives, you might want to research the best peptides for weight loss to understand how tirzepatide compares to other options.
